Eminyakeni yamuva, into ebizwa ngokuthiI-Nicotinamide Riboside(NR) idonse ukunaka okusabalele emphakathini wesayensi kanye nomkhakha wezempilo. I-NR iyisandulela sikavithamini B3 futhi ibhekwa njengamandla okulwa nokuguga nokunakekelwa kwezempilo, futhi isiba indawo eshisayo yocwaningo nentuthuko.
NRkutholwe ukwandisa amazinga e-intracellular e-NAD+, i-coenzyme ebalulekile ehilelekile ekulawuleni umzimba weselula nokukhiqizwa kwamandla. Njengoba iminyaka ikhula, amazinga e-NAD+ emzimbeni womuntu ehla kancane kancane, futhi ukwesekwa kwe-NR kungasiza ekugcineni amazinga e-NAD+ aphezulu, okulindeleke ukubambezeleka inqubo yokuguga futhi kuthuthukise ukusebenza kwamaseli.
Ngaphezu kwekhono layo lokulwa nokuguga,NRkutholakale ukuthi kunemiphumela emihle empilweni yenhliziyo nemithambo yegazi, impilo ye-metabolic, kanye ne-neuroprotection. Ucwaningo lukhombisa ukuthi i-NR ingathuthukisa ukusebenza kwemithambo yegazi, inciphise amazinga e-cholesterol, inciphise izimpendulo zokuvuvukala, futhi ibe nezinzuzo ezingaba khona ekuvimbeleni isifo senhliziyo. Ngaphezu kwalokho, i-NR kukholakala ukuthi isiza ukulawula amazinga kashukela egazini, ithuthukise ukuzwela kwe-insulin, futhi ibambe iqhaza ekuvimbeleni isifo sikashukela nokukhuluphala. Mayelana ne-neuroprotection, i-NR itholakale ithuthukisa ukukhiqizwa kwamandla kwamangqamuzana obuchopho futhi kulindeleke ukuthi ibambe iqhaza elihle ekuvimbeleni izifo ze-neurodeergenerative.
Njengoba ucwaningo nge-NR luqhubeka nokujula, izinkampani eziningi zemikhiqizo yezempilo seziqala ukwengeza i-NR njengesithako esiyinhloko emikhiqizweni yezempilo ukuze kuhlangatshezwane nezidingo zabantu zokulwa nokuguga nokunakekelwa kwezempilo. Ngesikhathi esifanayo, ezinye izivivinyo zomtholampilo nazo ziyaqhubeka ukuze kuqinisekiswe ukusebenza kahle nokuphepha kwe-NR emikhakheni ehlukahlukene yezempilo.
NakubaNRinamandla amakhulu, ucwaningo olwengeziwe luyadingeka ukuze kuqinisekiswe imiphumela yayo yesikhathi eside nokuphepha. Ngaphezu kwalokho, abantu badinga futhi ukukhetha imikhiqizo ye-NR ngokucophelela ukuze baqinisekise ukuthi imithombo yabo nekhwalithi ithembekile. Njengoba ucwaningo nokuthuthukiswa kwe-NR kuqhubeka nokujula, ngikholwa ukuthi kuzoletha impumelelo entsha nethemba empilweni yabantu.
Isikhathi sokuthumela: Aug-29-2024
