I-Newgreen Supply Pharmaceutical 99% Purity Metallothionein Powder Material Metallothionein Mt Rabbit Liver Zinc Metallothionein
Incazelo Yomkhiqizo
I-Metallothionein iyiphrotheni enesisindo samangqamuzana ephansi enekhono lokubopha insimbi kanye nezakhiwo eziphakeme zokungeniswa. [1] Ama-peptide amafushane anothe nge-cysteine anokuhlobana okuphezulu kwezinhlobonhlobo zezinsimbi ezisindayo. Iphrotheni enesisindo esiphansi samangqamuzana nokuqukethwe okuphezulu kakhulu kwezinsalela ze-cysteine nezinsimbi. Izinsimbi ezihlanganisiwe ngokuyinhloko ziyi-cadmium, ithusi ne-zinc, ezitholakala kakhulu ezintweni eziphilayo ezihlukahlukene kusukela kumagciwane amancane kuya kubantu, futhi ukwakheka kwazo kulondolozwa kakhulu.
I-COA
| IZINTO | IZINGA | UMPHUMELA WOKUHLOLA |
| Isivivinyo | 98%min Metallothionein | Kuyavumelana |
| Umbala | Impushana Emhlophe | Kuyavumelana |
| Iphunga | Alikho iphunga elikhethekile | Kuyavumelana |
| Usayizi wezinhlayiya | I-100% idlula i-80mesh | Kuyavumelana |
| Ukulahlekelwa ekomisweni | ≤5.0% | 2.35% |
| Izinsalela | ≤1.0% | Kuyavumelana |
| Insimbi enzima | ≤10.0ppm | 7 ppm |
| As | ≤2.0ppm | Kuyavumelana |
| Pb | ≤2.0ppm | Kuyavumelana |
| Izinsalela zezibulala-zinambuzane | Okubi | Okubi |
| Inani lepuleti eliphelele | ≤100cfu/g | Kuyavumelana |
| Imvubelo & Isikhunta | ≤100cfu/g | Kuyavumelana |
| E.Coli | Okubi | Okubi |
| I-Salmonella | Okubi | Okubi |
| Isiphetho | Vumelanisa ne-Specification | |
| Isitoreji | Igcinwe Endaweni Epholile Neyomile, Zigcine Kude Nokukhanya Okuqinile Nokushisa | |
| Impilo yeshelufu | Iminyaka emi-2 lapho igcinwe kahle | |
Umsebenzi
I-MT iyiphrotheni ebopha insimbi ecebile nge-cysteine. Iqembu layo le-sulfhydryl lingakwazi ukuhlafuna izinsimbi ezinobuthi kakhulu futhi lizikhiphe emzimbeni, ngaleyo ndlela lifinyelele ekukhishweni kobuthi. [4] I-MT ihlobene ne-metabolism yezinsimbi zokulandelela. Kuzo zonke izicubu ezincelisayo, i-MT-1 ne-MT-2 zivezwa ngokuvumelana. I-MT-3 iyilungu elithile lobuchopho kulo mndeni. Ingabopha i-zinc nethusi futhi inemisebenzi ebalulekile ye-neurophysiological kanye ne-neuromodulation. Ucwaningo lwezinto eziphilayo eziningi zasemanzini luye lwabonisa ukuthi i-MT idlala indima ebalulekile ekulawuleni izakhi zensimbi eziyisisekelo, futhi inemiphumela evimbelayo kanye ne-detoxifying ezintweni zensimbi ezingezona eziyisisekelo. I-MT inganciphisa ngempumelelo ubuthi bezinsimbi ezisindayo emzimbeni ngokuhlanganisa nezinsimbi ezisindayo, futhi njengamanje iyikhambi elifaneleka kakhulu le-biological chelating ekusebenzeni komtholampilo.
Ukuvikelwa kwemvelo
Ngokusebenzisa izici zenhlanganisela ye-MT nensimbi, kungenzeka ukuzalanisa noma ukusebenzisa ubunjiniyela bezakhi zofuzo ukuze kusungulwe uhlelo oluphezulu lokubonisa lwe-MT ukulawula ukungcoliswa kwensimbi esindayo. Ngokwemibiko, ugwayi otheleleke nge-yeast MT gene ungakhuphula kakhulu ukumuncwa kwe-cu2 enhlabathini engcolile, futhi le ndlela ingasetshenziswa ukulungisa izindawo ezingcoliswe izinsimbi ezinzima.
I-MT kanye nokumelana nemisebe
Imisebe ye-ionizing ingakhiqiza inani elikhulu lama-radicals mahhala, angalimaza izinto eziphilayo ngokuqondile noma ngokungaqondile. Ucwaningo luye lwabonisa ukuthi ukuphathwa komlomo kwe-MT kungandisa isikhathi sokusinda samagundane avezwe emisebeni ye-ionizing ye-dose ephezulu yesikhathi esisodwa, futhi kunciphise ukulimala kwamasosha omzimba okubangelwa umthamo wesikhathi esisodwa kanye nemithamo eminingi ephansi ye-ionizing. . I-Oral MT ingamunca inani elikhulu lamaCys angena emzimbeni. Ihlinzeka ngezinto zokusetshenziswa zokulungisa amabhondi e-disulfide aphulwa ngemisebe emzimbeni.
Isifo se-MT kanye ne-Parkison (PD).
Ukuhlola okuningi kuye kwafakazela ukuthi i-MT inomphumela ovikelayo ohlelweni lwezinzwa. Ukuhlola kubonise ukuthi kumagundane e-transgenic, ukucindezeleka ngokweqile kwe-MT-1 kungashintsha izimpawu ze-encephalitis futhi kukhuthaze ukulungiswa kobuchopho. Kuyisici esivikelayo kumangqamuzana ezinzwa. Ngocwaningo lwemodeli yokugwaza amagundane kanye nemodeli ye-ischemia, kutholakala ukuthi i-MT-3 ihileleke ekulungiseni umonakalo wesistimu yezinzwa ezimaphakathi. Isifo se-PD sibangelwa ukufakwa kwama-radicals mahhala nge-6-hydroxydopamine, kanye nama-inducers athile we-MT isoforms ebuchosheni, njengokucindezeleka kwe-oxidative, ama-cytokines kanye nezinqubo zokuvuvukala, angavimbela le neurotoxicity, ekhululekile ku-MT clearance Base ehlobene.
Izinhlelo zokusebenza
I-Metallothionein (MT) iwuhlobo lwephrotheni ephansi yamangqamuzana acebile nge-cysteine nensimbi. Ngenxa yekhono layo lokubopha inani elikhulu lama-ion ensimbi kanye nomsebenzi walo okhethekile wokuphila, liye lanakwa kakhulu emkhakheni we-biochemistry. Umlando wocwaningo lwe-MT usuneminyaka engaphezu kwengu-40, futhi ucwaningo ngesakhiwo sayo, izici, ukulawulwa kwezakhi zofuzo kanye nomsebenzi wezinto eziphilayo belulokhu lujula ngokujulile. Amathemba okufaka isicelo e-MT abanzi kakhulu, afaka kodwa awakhawulelwe kulokhu:
1. Inkambu yezokwelapha : I-MT isetshenziswa kakhulu emtholampilo ezifweni zenhliziyo nemithambo yegazi kanye nezimila, kodwa ayizange isetshenziswe esithuthwaneni.
2. Impilo yokudla kanye nesengezo sezimonyo : I-MT ingasetshenziswa njengesengezo ekudleni, izithasiselo zezempilo nezimonyo ukunikeza izinzuzo zezempilo ezengeziwe.
3. I-Genetic engineering reagent : Kubunjiniyela bezakhi zofuzo, i-MT isetshenziswa njenge-reagent ukukhuthaza ucwaningo nokusebenzisa ubunjiniyela bofuzo.
4. Ukuvikelwa kwamakhemikhali nemvelo : I-MT isetshenziswa nasezinkundleni zokuvikela amakhemikhali nezemvelo, isibonelo ukususa izinsimbi eziyingozi.
izindatshana zaselabhorethri yezolimo : I-MT ingasetshenziswa njengendatshana yokuhlola ocwaningweni lwezolimo, ikakhulukazi ocwaningweni lokunukubezeka kwensimbi enzima kanye nokubekezelela izitshalo ezinsimbi ezisindayo.
5. Ngaphezu kwalokho, i-MT iphinde ibe nomsebenzi wokubamba iqhaza ekugcinweni, ekuthuthweni nasekusetshenzisweni kwe-trace elements i-zinc nethusi, i-detoxification ye-heavy metal elements i-cadmium, i-mercury ne-lead, imisebe ye-ionizing ephikisanayo nokukhipha amaqembu angenayo i-hydroxyl. Izakhi zofuzo zemvelo ze-MT zenziwe zakhiwe ugwayi, i-petunia nezinye izitshalo ngobunjiniyela bezakhi zofuzo, futhi izitshalo ze-transgenic zibonise ukumelana okuphezulu nokungcola kwe-cadmium. Uma isakhi sofuzo se-MT sidluliselwa ku-clover kanye ne-duckweed bese sitshalwa emhlabeni noma emanzini angcoliswe i-cadmium ne-mercury, singamunca inani elikhulu lezinsimbi ezinobuthi emhlabathini nasemanzini, futhi sibambe iqhaza ekususeni izinsimbi eziyingozi .
Imikhiqizo Ehlobene:
Imboni ye-Newgreen iphinde inikeze ama-amino acid njengokulandelayo:
Iphakheji Nokulethwa
