I-Newgreen Supply High Quality Kelp Extract 20% ye-Fucoxanthin Powder

1. Umphumela wokulwa nesimila

(1) Umdlavuza wesikhumba

I-Fucoxanthin ivimbele ukuthuthukiswa komsebenzi we-ornithine decarboxylase esikhumbeni se-epidermal segundane esidalwe yi-tetradecanoylphorbol-13-acetate (TPA), futhi ukhokho wavimbela ukusebenza kwe-herpesvirus yomuntu ebangelwa yi-TPA, ngaleyo ndlela ivimbele izimila zesikhumba ezibangelwa i-TPA.

(2) Umdlavuza wekoloni

I-Fucoxanthin ingavimbela ukwakheka kwe-duodenal carcinoma ebangelwa i-n-ethyl-N '-nitro-n-nitroguanidine. I-Fucoxanthine ivimbele kakhulu ukukhula kwemigqa yamaseli omdlavuza wekoloni, okuhlanganisa i-Caco-2, HT-29 kanye ne-DLD-1. Ingadala ukwephuka kwe-DNA yamaseli omdlavuza wekoloni, ikhuthaze i-apoptosis yamaseli, futhi ivimbele ukuvezwa kwephrotheni ehlobene ne-apoptosis i-Bcl-2.

I-Fucoxanthin inganqanda ukwanda komugqa wamaseli womdlavuza wekholoni womuntu i-WiDr ngendlela encike kumthamo, futhi ingavimba umjikelezo weseli esigabeni se-G0/G1 futhi yenze i-apoptosis.

(3) Izimila ze-Hematological

Umthelela we-fucoxanthin kumugqa weseli we-HL-60 we-acute myeloid leukemia. I-Fucoxanthin ingavimbela ngokuphawulekayo ukwanda kwamaseli e-HL-60. Umthelela we-fucoxanthin ku-T lymphocytic leukemia yabantu abadala. I-Fucoxanthin kanye ne-metabolite fucoxanol yayo ivimbela ukusinda kwamaseli e-T atheleleke ngegciwane le-T-cell lymphotropic virus uhlobo 1 (HTLV-1) kanye namaseli e-T-cell leukemia yabantu abadala.

(4) Umdlavuza wendlala yesinye

I-Fucoxanthin inganciphisa kakhulu izinga lokusinda kwamangqamuzana omdlavuza wendlala yesinye futhi yenze i-cell apoptosis. I-Fucoxanthin kanye ne-metabolite fucoxanol yayo ingavimbela ukwanda kwamaseli e-PC-3, isebenze i-Caspase-3 futhi yenze i-apoptosis.

(5) Umdlavuza wesibindi

I-Fucoxanthoxanthine ingavimbela ukukhula kwamaseli e-HepG2, ivimbele iseli esigabeni se-G0/G1, futhi ivimbele i-Rb protein phosphorylation endaweni ye-Ser780.

2.Umphumela we-Antioxidant

I-Fucoxanthin inomphumela omuhle we-antioxidant, ongcono nakakhulu kunovithamini E novithamini C. I-Fucoxanthin inomphumela wokuvikela ekulimaleni kwe-fibrocyte yomuntu okubangelwa i-UV-B. Umsebenzi we-antioxidant we-Fucoxanthin ikakhulukazi ngokulawulwa komsebenzi we-Na+-K+ -ATPase, kanye nokulawulwa komsebenzi we-catalase kanye ne-glutathione ezicutshini nama-molecule abangelwa ukushoda kwe-retinol. I-Fucoxanthin inenzuzo empilweni yamehlo, ikakhulukazi umphumela wayo wokuvikela ku-retina, okusiza ukuvimbela izifo zamehlo ezifana nolwelwesi lwama-macular kanye nokuwohloka kwe-macular.

3.Umphumela wokulwa nokuvuvukala

I-Fucoxanthin ivimbele ukukhishwa kwe-endotoxin-induced mediators ukuvuvukala ngendlela encike kumthamo, futhi umphumela wayo wokulwa nokuvuvukala wawuqhathaniswa ne-prednisolone, okubonisa ukuthi i-fucoxanthin yayinemiphumela ethile yokuvimbela ukungena kokuvuvukala okubangelwa i-endotoxin, NO, PGE2 kanye ne-tumor necrosis factor amagundane. Umphumela wayo wokulwa nokuvuvukala ikakhulukazi ngokuvimbela ukukhishwa kwe-NO ekuphenduleni kokuvuvukala okubangelwa ama-macrophages enziwe yi-LPS. Ukuhlaziywa kwe-RT-PCR kubonise ukuthi i-mRNA ye-NO synthetase ne-cyclooxygenase yayivinjelwe i-fucoxanthin, kanye nokuvezwa kwe-tumor necrosis factor, i-leukocyte interleukin IL-1β ne-IL-6, kanye ne-mRNA viability factor yavinjelwa i-fucoxanthin. Le miphumela iphakamisa ukuthi i-fucoxanthin ingase idlale indima ebalulekile ekuphenduleni okuhlukahlukene kokuvuvukala.

4.Yehlisa isisindo

I-Fucoxanthin ingaqeda ukuqoqwa kwamafutha ngezindlela ezimbili. I-Fucoxanthin yenza kusebenze iphrotheni ebizwa ngokuthi i-UCP1, ekhuthaza i-lipolysis. Iphinde ikhuthaze isibindi ukuthi sikhiqize i-DHA, eyehlisa amazinga e-cholesterol.

5. Okunye

Ama-sea urchins aqukethe i-fucoxanthin ekudleni kwawo izimila zasolwandle, edlala indima ebalulekile ku-phagocytosis yama-macrophages kanye ne-ovulation.